Reversible Posterior Leukoencephalopathy Syndrome with Microscopic Polyangiitis

Reversible posterior leukoencephalopathy syndrome.

Reversible Posterior Leukoencephalopathy Syndrome

Hinchey et al used the term „reversible posterior leukoencephalopathy syndrome“ in 1996 to describe a syndrome characterized by headache, confusion, seizures and vision disturbances, including cortical blindness, connected with reversible changes on brain magnetic resonance imaging (MRI) which pointed to the white matter eodema, predominantly in the posterior brain regions (1). Initially, this ...

Posterior Reversible Leukoencephalopathy Syndrome Associated with Pazopanib

A 62-year-old female patient with metastatic renal cell carcinoma under third-line treatment with pazopanib for 8 weeks suddenly developed severe headaches, grand mal seizures and paresis of the left arm in combination with gait instability as well as nausea and vomiting during her vacation abroad. The emergency physician measured systolic blood pressure values over 300 mm Hg and suspected a st...

Posterior reversible leukoencephalopathy syndrome after kratom ingestion.

Posterior reversible encephalopathy syndrome has been associated with hypertension, preeclampsia, cancer chemotherapy, and drugs of abuse, such as amphetamine and methamphetamine. We report a young man who suddenly developed severe headache, disorientation, and aphasia following ingestion of kratom and Adderall. Computed tomography and magnetic resonance imaging of his head revealed foci of vas...

Clinical spectrum of reversible posterior leukoencephalopathy syndrome.

BACKGROUND Reversible posterior leukoencephalopathy syndrome (RPLS) is characterized by neuroimaging findings of reversible vasogenic subcortical edema without infarction. The clinical syndrome of RPLS typically involves headache, encephalopathy, visual symptoms, and seizures. OBJECTIVE To retrospectively identify patients with RPLS with a characteristic clinical presentation and neuroimaging...